Paper

Design and evaluation of piperidine carboxamide derivatives as potent ALK inhibitors through 3D-QSAR modeling, artificial neural network and computational analysis

Published Jun 1, 2024 · DOI · Ya‐kun Zhang, Jianbo Tong, M. Luo

Arabian Journal of Chemistry

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Study Snapshot

Piperidine carboxamide derivatives show promise as potent ALK inhibitors, with a lead compound selected for its high inhibitory activity and drug-likeness.

Population
Older adults (50-71 years)
Sample size
24
Methods
Observational
Outcomes
Body Mass Index projections
Results
Social networks mitigate obesity in older groups.

Design and evaluation of piperidine carboxamide derivatives as potent ALK inhibitors through 3D-QSAR modeling, artificial neural network and computational analysis

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