Paper

Synthesis of 1,3,5-triphenyl-1,2,4-triazole derivatives and their neuroprotection by anti-oxidative stress and anti-inflammation and protecting BBB.

Published Aug 1, 2023 · DOI · Yang Wang, Ruiqi Su, Jian-Wen Chen

European journal of medicinal chemistry

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Abstract

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Non-RCTAnimal Study

Study Snapshot

Compound 9 shows potential in neuroprotection against acute ischemic stroke by inhibiting oxidative stress, neuroinflammation, and protecting the blood-brain barrier, making it a promising stroke treatment candidate.

Population
Older adults (50-71 years)
Sample size
24
Methods
Observational
Outcomes
Body Mass Index projections
Results
Social networks mitigate obesity in older groups.

Synthesis of 1,3,5-triphenyl-1,2,4-triazole derivatives and their neuroprotection by anti-oxidative stress and anti-inflammation and protecting BBB.

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