Paper

mTOR Inhibition limits LPS induced acute kidney injury and ameliorates hallmarks of cellular senescence

Published Mar 20, 2025 · A. Stasi, R. Franzin, Fabio Sallustio

Scientific Reports

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Abstract

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Non-RCTAnimal Study

Study Snapshot

Rapamycin effectively reduces kidney injury and slows the progression of chronic kidney disease in mice models of LPS-induced acute kidney injury.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

mTOR Inhibition limits LPS induced acute kidney injury and ameliorates hallmarks of cellular senescence

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